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Experience

Oncology Tumor Experience
 
51 Oncology trials conducted since 2001
Total of 6,398 patients accrued
Trials conducted:
  Phase I – 2 trials
  Phase II – 22 trials
  Phase III – 15 trials
  Phase IV – 6 trials
  Tumor Types include:
    Breast
    CLL
    NSCLC
    Non Hodgkin’s Lymphoma
    Colorectal
    Hodgkin’s Lymphoma
    Prostate
    Melanoma
    SCLC
    Multiple Myeloma
    Renal
    MDS
    Head & Neck
    Glioblastoma
    Bone Mets
Tumor Experience
 
CANCER Phase Number of Patients Number of Sites Year
Breast cancer IV 300 70 2001
Breast--1st line Met II 51 21 2003
Breast--1st line Met II 72 29 2004
Breast--Adjuvant ER+ III 117 8 2006
Breast--2nd line Met III 7 14 2006
Breast--1st line Met III 17 14 2006
Breast--1st line Met II 10 15 2007
Breast--1st line Met II 3 14 2008
Breast 1st/2nd line Met II 0 5 2008
NSCLC II b 110 20 2003
NSCLC 1st line II 82 21 2004
NSCLC 2nd line II 7 9 2004
NSCLC 1st line II 69 22 2005
NSCLC 2nd line II 70 20 2005
NSCLC 1st line II 43 29 2006
Lung Epidemiology 3000 65 2006
NSCLC 1st line III 15 4 2006
Advanced NSCLC II 10 8 2007
NSCLC 2nd & 3rd line III 6 12 2007
SCLC 2nd line III 5 9 2008
Rectum II 87 16 2003
Colorectal--1st line Met II 82 19 2004
Colorectal--1st line Met III 57 31 2205
Colorectal--2nd line Met II 29 39 2006
Prostate III a 250 50 2002
Prostate IV 160 50 2003
Prostate IV 85 12 2004
HRPC--1st line II 35 22 2006
Prostate Epidemiology 120 1 2007
Prostate II a 24 6 2007
HRPC--1st line III 11 10 2007
Prostate--2nd line Met or beyond EAP 40 16 2007
Kidney I 10 5 2004
Renal cell--1st line Met III 41 11 2006
Kidney Epidemiology 35 1 2008
Hodgkins Lymphoma I 15 1 2006
NHL III 320 42 2007
CLL IV 210 25 2007
MDS II 15 13 2004
Biliary tract II 61 6 2003
Melanocarcinoma II a 152 2 2007
Melanoma II 7 8 2007
Cancer Pharmacovigilance N/A N/A 2007
Head and Neck Investigator-initiated study 75 1 2007
Glioblastoma IV 150 12 2000
Myeloma IV 300 60 2001
Multiple Myeloma –1st line IIIb 7 17 2007
Supportive Care--Antiemetic Breast, NSCLC, Colon II 33/16 14 2006
Supportive Care--NSCLC Chemo-induced Thrombocytopenia III 0 5 2006
Supportive Care—Breast, Bone Met III 3 12 2006
Supportive Care--Bone Mets III 23 8 2006
 
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